New drug ‘could save the hearing of millions’

The researchers behind a new study published in the Journal of Experimental Medicine note that inhibiting an enzyme known as cyclin-dependent kinase 2 could potentially save the hearing of millions of people. Researchers suggest that the drug kenpaullone may help to prevent hearing loss. In the study, inhibiting cyclin-dependent kinase 2 (CDK2) was found to protect rodents from noise- and drug-related hearing loss by preventing the death of inner ear cells. If CDK2 inhibitors are proven to be an effective treatment for this purpose in humans, it would be very significant, as there are no…

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Has Marketing Automation Started Making Sense?

B2B marketing automation has a long way to go, suggest the results of a recent survey of more than 350 marketing professionals in the United States and Europe. Act-On Software commissioned Econsultancy to conduct the research for its State of B2B Marketing report released last week. Only 51 percent of respondents said the CMO or equivalent took a keen interest in marketing automation, and just 37 percent said the issue got executive support outside the marketing department. Among the other key findings: Only 27 percent of the respondents strongly agreed that marketing…

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The Painfully Persistent B2B Sales and Marketing Divide

The historical sales and marketing team divide has been getting worse, suggests a B2B report InsideView released this week. A disconnect between sales and marketing can have a direct impact on companies’ top and bottom lines. The 995 United States-based sales and marketing professionals who responded to the InsideView survey came from a cross-section of industries throughout the country. Fifty percent of the respondents were in sales and 40 percent were in marketing, with the remaining 10 percent classified as “other.” They represented a range of company sizes, from small businesses to…

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Japan’s northernmost island of Hokkaidō

Japan’s northernmost island of Hokkaidō is best known for two things: winter sports and Sapporo beer. But the little-known eastern side of the island is a dream escape at any time of year for the adventurous visitor, whether you’re into beer or not. In eastern Hokkaidō wildlife wonders abound (is that a bear snacking on freshly caught salmon?); there are lakes, sulphur-spewing volcanoes and hot springs aplenty; and there’s an indigenous culture trying to reassert itself after years of decline. Plus, all this comes with very few tourists. Here are…

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